p53 is found mutated in more than 50% of human cancers. Its familial syndrome is the Li-Fraumeni Syndrome. p53 is found on chromosome 17p13.1 and has a crucial role in regulating the cell cycle and mediating apoptosis when the cell is beyond repair. Mutated p53 equals a very aggressive tumor.
Antibody (2)Assay (2)Kit (0) | Protein (0)Review (2) |
PR: 4
| p53 Pathway - http://jcs.biologists.org/cgi/reprint/114/23/4139.pdf p53 Pathway and p53 Functions. - [Read more] |
PR: 3
| p53 iRNA - http://www.promega.com/cnotes/cn007/cn007_12.pdf p53 iRNA interference. - [Read more] |
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